Rajesh Seenivasan pic

Rajesh Seenivasan, Ph.D. Chemistry, 2011, Madurai Kamaraj University, India

Research Associate

Enzyme Institute Building

Room 472
1710 University Ave
Madison, WI   53726
Tel: (608) 265-6737
Fax: (608) 262-1228
E-mail: rajesh.seenivasan@wisc.edu

 

Program Affiliations

Biological Systems Engineering

Education and Certificates

Ph.D. Chemistry, 2011, Madurai Kamaraj University, India.
M.Phil. Chemistry, 2004, ANJA College affiliated to Madurai Kamaraj University, India.
M.Sc. Chemistry, 2002, SRNM College affiliated to Madurai Kamaraj University, India.
B.Sc. Chemistry, 2000, SRNM College affiliated to Madurai Kamaraj University, India.

Fields of Interest

Synthesis of novel nanoparticles and nanomaterials
Biosensor and Bioimaging
Nanosensor design and instrumentation
Microfluidic electrochemical sensor platforms
Oxidative stress, cancer biomarkers, foodborne pathogens and toxins detection

Publications

Prakash, S., Rajesh, S., Rajasingh, S., Karunakaran, C., and Vasu, V. 2012. Electrochemical incorporation of hemin in a ZnO–PPy nanocomposite on a Pt electrode as NOx sensor. Analyst 137:5874–5880.

 

Madasamy, T., Pandiaraj, M., Kanugula, A.K., Rajesh, S., Bhargava, K., Sethy, N.K., Kotamraju, S., and Karunakaran, C. 2012. Gold nanoparticles with self-assembled cysteine monolayer coupled to nitrate reductase in polypyrrole matrix enhanced nitrate biosensor. Advanced Chemistry Letters – In Press.

 

Gurusamy, P., Muthukumar, K., Rajesh, S., Muneeswaran, G., Perumal, S., and Karunakaran, C. 2012. “Theoretical investigation of quinone metabolites of dopamine interaction with DNA – insights into toxicological effects”. Journal of Structural Biology 180:125–131.

 

Rajasingh, S., Prakash, S., Muneeswaran, G., Rajesh, S., Muthukumar, K., Vasu, V., and Karunakaran, C. 2012. “Molecular dynamics simulation studies on structural and conformational changes in tyrosine - 67 nitrated cytochrome c”. Molecular Simulation 38:459–467.

 

Prakash, S., Rajesh, S., Singh, S.K., Ilavazhagan, G., Vasu, V., and Karunakaran, C. 2011. “Copper nanoparticles entrapped in SWCNT-PPy nanocomposite on Pt electrode as NOx electrochemical sensor”. Talanta 85:964–969.

 

Rajesh, S., Sethy, N.K., Kalpana, B., Ilavazhagan, G., Singh, S.K., and Karunakaran, C. 2011. “Electrochemical sensor for simultaneous measurement of nitrite and superoxide anion radical using superoxide dismutase-mimetic manganese(III) tetrakis(1-methyl-4-pyridyl) porphyrin on polypyrrole matrix”. Sensor Letters 9:1682–1688.

 

Prakash, S., Rajesh, S., Singh, S.K., Kalpana, B., Ilavazhagan, G., Vasu, V., and Karunakaran, C. 2011. “Electrochemical incorporation of manganese(III) tetrakis(1-methyl-4-pyridyl) porphyrin in ZnO-PPy nanocomposite on Pt electrode as NOx sensor”. Sensor Letters 9: 1623–1628.

 

Rajesh, S., Kanugula, A.K., Kalpana, B., Ilavazhagan, G., Kotamraju, S., and Karunakaran, C. 2010. “Simultaneous electrochemical determination of superoxide anion radical and nitrite using Cu,ZnSOD immobilized on carbon nanotube in polypyrrole matrix”. Biosensors and Bioelectronics 26:689–695.

 

Nilakantan, V., Liang, H.L., Rajesh, S., Mortensen, J., and Karunakaran, C. 2010. “Time-dependant protective effects of mangenese(III) tetrakis (1-methyl-4-pyridyl) porphyrin on mitochondrial function following renal ischemia-reperfusion injury”. Free Radical Research 44:773–782.

 

Rajesh, S., Arivudainambi, U.S.E., Rajasingh, S., Rajendran, A., Kotamraju, S., and Karunakaran, C. 2010. “Superoxide anion radical biosensor using self-assembled cysteine monolayer on gold nanoparticles in polypyrrole matrix facilitated electron transfer in Cu,ZnSOD”. Sensor Letters 8:613–621.

 

Rajesh, S., Dharmapandian, P., Rajasingh, S., Rajendran, A., and Karunakaran, C. 2010. “Electrochemical cysteine biosensor based on the selective oxidase-peroxidase activities of copper, zinc superoxide dismutase”. Sensor Actuator B 148:17–22.

 

Prakash, S., Rajasingh, S., and Rajesh, S. 2009. “Ab initio study of 7-methoxyl -4’- hydroxyisoflavone”. Asian Journal of Spectroscopy 13:39–40.

Selected Awards and Honors

Junior Research Fellowship, Department of Biotechnology, India.

Expertise Summary

Dr. Rajesh’s research interests are focused on 1) synthesis and characterization of novel metal nanoparticles, metal oxide nanoparticles, self-assembled nanoparticles and functionalized nanomaterials and 2) fabrication, characterization, and development of highly sensitive biosensor / sensor using enzyme and its mimetic immobilized nanocomposite electrode for oxidative stress, cancer biomarkers, foodborne pathogens and toxins detection. He has published 12 research articles, 11 conference papers and 2 Indian patents. One of his articles was highlighted in Nature India magazine entitled as “Nanotube Sensor”. Further, he continued to work as a research associate in Dr. C. Karunakaran’s lab, Department of Chemistry, VHNSN College (affiliated to Madurai Kamaraj University), Virudhunagar, Tamilnadu, India from 2010 to 2011. After that, he got Assistant Professor Job in Department of Biotechnology, MEPCO Engineering College, Sivakasi, Tamilnadu, India in the year of 2011. Later, he joined as a volunteer postdoctoral researcher in Dr. Clemens Burda’s Lab, Department of Chemistry, Case Western Reserve University, Cleveland, Ohio, USA from 2012 to 2013.